After isolation and description, microbiological material is typically deposited in Biological Resource Centers (BRCs) to make it available for the scientific community. These BRCs distribute the material to individual researchers and other collections. Each transfer imposes a risk of contamination or human mistake, and thus of possibly confusing scientific results. In order to check the validity of strains, we need to reconstruct their exchange history ('Histri'). A histri consists of all known strain numbers for the given strain, annotated with extra information about each deposit (previous strain number, depositor, date,…) visualized in a tree. The diagram is read from top to bottom. That way, it is easy to determine which lineages are possibly affected and to mark affected literature, sequences or other scientific results, if necessary.
The diagram is read from top to bottom. The star indicates the original isolate. Thick lines indicate additional information on the transfer (e.g. date and depositor), dashed lines express “institutional transfers” (acronym changes, collection merges, etc.). All strain numbers in the gray box under the diagram have an unknown exchange history.
Histris are reconstructed using the Histri Editor. You can lauch the Histri Editor from Strain Passport and 'Make Histri' pages after logging in.
The Make Histri project was launched to start a human curation process of bacterial and archaeal type strains. The project is hosted on a separate homepage which lists all type strains needing curation. Extra statistics and previous revisions are also available. Histris edited via the 'Make Histri' project home page are immediately available from the corrsponding strain passports (and vice versa).